MovDisordV3, Main, Exploration, bibRecord, 003330

NR4A2 genetic variation in sporadic Parkinson's disease: A genewide approach

Identifieur interne : 003330 ( Main/Exploration ); précédent : 003329; suivant : 003331

NR4A2 genetic variation in sporadic Parkinson's disease: A genewide approach

Auteurs : Daniel G. Healy [Royaume-Uni] ; Patrick M. Abou-Sleiman [Royaume-Uni] ; Kourosh R. Ahmadi [Royaume-Uni] ; Sonia Gandhi [Royaume-Uni] ; Miratul M. Muqit [Royaume-Uni] ; Kailash P. Bhatia [Royaume-Uni] ; Niall P. Quinn [Royaume-Uni] ; Andrew Lees (neurologue) [Royaume-Uni] ; Janice L. Holton [Royaume-Uni] ; Tamas Revesz [Royaume-Uni] ; Nicholas W. Wood [Royaume-Uni]

Source :

Movement Disorders [ 0885-3185 ] ; 2006-11.

RBID : ISTEX:EEFA5761E088010B56FFB73B63C384F2FF39A67F

Descripteurs français

Pascal (Inist)
- Haplotype, Marquage, Parkinson maladie, Sporadique, Système nerveux pathologie, Voie abord.

English descriptors

KwdEn :
- Case-Control Studies, Chi-Square Distribution, DNA-Binding Proteins (genetics), Female, Gene Frequency, Genetic Predisposition to Disease, Genetic Variation, Genotype, Haplotype, Humans, Male, Middle Aged, NR4A2, Nervous system diseases, Nuclear Receptor Subfamily 4, Group A, Member 2, Parkinson Disease (genetics), Parkinson disease, Parkinson's disease, Sporadic, Surgical approach, Tagging, Transcription Factors (genetics), genewide study, haplotype tagging.
MESH :
- chemical , genetics : DNA-Binding Proteins, Transcription Factors.
- genetics : Parkinson Disease.
- Case-Control Studies, Chi-Square Distribution, Female, Gene Frequency, Genetic Predisposition to Disease, Genetic Variation, Genotype, Humans, Male, Middle Aged, Nuclear Receptor Subfamily 4, Group A, Member 2.

Abstract

The NR4A2 gene, which may cause autosomal dominant Parkinson's disease (PD), has also been reported to be a susceptibility factor for sporadic PD. Here, we use a haplotype‐tagging approach in 802 PD patients and 784 controls and demonstrate that common genetic variation, including NR4A2 haplotypes, does not influence the risk of PD in the Caucasian population. © 2006 Movement Disorder Society

Url:

https://api.istex.fr/document/EEFA5761E088010B56FFB73B63C384F2FF39A67F/fulltext/pdf

DOI: 10.1002/mds.21018

Affiliations:

Le document en format XML

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<term>Gene Frequency</term>
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<front><div type="abstract" xml:lang="en">The NR4A2 gene, which may cause autosomal dominant Parkinson's disease (PD), has also been reported to be a susceptibility factor for sporadic PD. Here, we use a haplotype‐tagging approach in 802 PD patients and 784 controls and demonstrate that common genetic variation, including NR4A2 haplotypes, does not influence the risk of PD in the Caucasian population. © 2006 Movement Disorder Society</div>
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Movement Disorders (revue)

NR4A2 genetic variation in sporadic Parkinson's disease: A genewide approach

NR4A2 genetic variation in sporadic Parkinson's disease: A genewide approach

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Movement Disorders (revue)
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